发明名称 |
Substituted Pyrazoles as Modulators of Chemokine Receptors |
摘要 |
Substituted pyrazole compounds such compounds represented by formula I: which are used to modulate the CCR-2 chemokine receptor to prevent or treat inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis; and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions.
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申请公布号 |
US2008167322(A1) |
申请公布日期 |
2008.07.10 |
申请号 |
US20060884325 |
申请日期 |
2006.02.14 |
申请人 |
PINKERTON ANTHONY B;CUBE ROWENA;HUTCHINSON JOHN;HUANG DEHUA;VERNIER JEAN-MICHEL;SHEN DONG-MING |
发明人 |
PINKERTON ANTHONY B.;CUBE ROWENA;HUTCHINSON JOHN;HUANG DEHUA;VERNIER JEAN-MICHEL;SHEN DONG-MING |
分类号 |
A61K31/497;A61K31/4155;A61K31/4439;A61P19/02;C07D231/10;C07D401/02 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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地址 |
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