| 摘要 |
The invention relates to a method for releasing a biological sample from a solid matrix substantially without disintegration of said biological sample by at least partially transferring the solid state of said matrix into a dissolved or liquid state by changing at least one physico-chemical property of the environment of said matrix, to a kit comprising at least one compound selected from reagent(s), enzyme(s), acid(s), and base(s), liquid(s), and solvent(s) for releasing a biological sample from a solid matrix substantially without disintegration of said biological sample by at least partially transferring the solid state of said matrix into a dissolved or liquid state by changing at least one physico-chemical property of the environment of said matrix, and to a kit comprising at least one enzyme for releasing a biological sample from a solid matrix comprising one or more of waxes, high molecular weight alkane hydrocarbons like paraffn, mcnoterpenes, sucrose, agarose, starch, chitin, peptides, proteins, pectins, agar, acidic polymethylacrylates, cellulose acetate, cellulose acetate phthalate, vinylacetate, polyvinyl acetate phthalate, hydmxypropyl methylcellulose-acetate succinate, alginates, copolymers of methacrylic acid and methylmethacrylate, copolymers of vinylacetate and methacrylic acid, and polyvinylacetatephthalate.substantially without disintegration of said biological sample by adding at least one enzyme and optionally at least one further compound selected from reagent(s), enzyme(s), acid(s), and base(s), liquid(s), and solvent(s) to said matrix. |
