COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE
摘要
The present dislcosure provides amide-based, non-nucleoside compounds having an inhibitory activity against endogenous polymerases, such as polymerase alpha and polymerase gamma. This disclosure further provides uses of treating hyperproliferative diseases or disorders, such as benign or malignant neoplasms, and more specifically cancers that are sensitive to inhibition of polymerase alpha and polymerase gamma.
申请公布号
WO2008080223(A1)
申请公布日期
2008.07.10
申请号
WO2007CA02367
申请日期
2007.12.28
申请人
MIGENIX INC.;CAMERON, DALE, RUSSELL;GUARNA, MARIA, MARTA;METLITSKAIA, LUBA
发明人
CAMERON, DALE, RUSSELL;GUARNA, MARIA, MARTA;METLITSKAIA, LUBA