| 发明名称 |
BINDING POLYPEPTIDES WITH OPTIMIZED SCAFFOLDS |
| 摘要 |
<p>The invention provides variant heavy chain variable domains (VH) with increased folding stability. Libraries comprising a plurality of these polypeptides are also provided. In addition, compositions and methods of generating and using these polypeptides and libraries are provided.</p> |
| 申请公布号 |
WO2007134050(A8) |
申请公布日期 |
2008.07.10 |
| 申请号 |
WO2007US68469 |
申请日期 |
2007.05.08 |
| 申请人 |
GENENTECH, INC.;BARTHELEMY, PIERRE A.;SIDHU, SACHDEV S. |
发明人 |
BARTHELEMY, PIERRE A.;SIDHU, SACHDEV S. |
| 分类号 |
C07K16/00;A61K39/395;C07K16/32;C12N5/10;C12N15/10;C12N15/13;C12N15/63 |
主分类号 |
C07K16/00 |
| 代理机构 |
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