发明名称 FUSED SUBSTITUTED AMINOPYRROLIDINE DERIVATIVE
摘要 <p>A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensiti vity to quinolone antibacterial agents, and which exhibits high safety and e xcellent pharmacokinetics. A compound represented by the formula (I) or a sa lt thereof, or a hydrate thereof. Specifically, a quinolone derivative of th e formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being b onded to a quinolone mother skeleton Q containing a pyridobenzoxazine struct ure.</p>
申请公布号 CA2674369(A1) 申请公布日期 2008.07.10
申请号 CA20072674369 申请日期 2007.12.28
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 NAGAMOCHI, MASATOSHI;MIYAUCHI, RIE;NAKAYAMA, KIYOSHI;TAKEMURA, MAKOTO;TSUDA, TOSHIFUMI;KOMORIYA, SATOSHI;YOSHIDA, KENICHI;TAKAHASHI, HISASHI;ODAGIRI, TAKASHI;INAGAKI, HIROAKI;KITAMURA, TAKAHIRO
分类号 C07D401/04;A61K31/47;A61P31/04;C07D401/14;C07D491/052;C07D498/04 主分类号 C07D401/04
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