| 发明名称 |
RECOMBINANT HUMAN FACTOR IX AND USE THEREOF |
| 摘要 |
The present invention aims at converting factor IX into a molecule with enhanced activity which provides an alternative for replacement therapy and gene therapy for hemophilia B. Using recombinant techniques, factor IX with replacement at positions 86, 277, and 338 exhibits better clotting activity than recombinant wild type factor IX.
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| 申请公布号 |
US2008167219(A1) |
申请公布日期 |
2008.07.10 |
| 申请号 |
US20070935779 |
申请日期 |
2007.11.06 |
| 申请人 |
LIN SHU-WHA;LIN CHIA-NI;WU HUA-LIN;SHI GUEY-YUEH |
发明人 |
LIN SHU-WHA;LIN CHIA-NI;WU HUA-LIN;SHI GUEY-YUEH |
| 分类号 |
A61K38/36;A61K48/00;C07H21/00;C07K14/745 |
主分类号 |
A61K38/36 |
| 代理机构 |
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