发明名称 MULTIDRUG MULTILIGAND CONJUGATES FOR TARGETED DRUG DELIVERY
摘要 Described is a multi drug multiligand conjugate for targeted drug delivery. The MDML conjugate contains a plurality of tripartite molecules linked to a central scaffold moiety, with each tripartite molecule comprising a targeting molecule, a therapeutic agent and a scaffold binding element. The MDML conjugate allows for more efficient delivery of therapeutic agents to the cells resulting in enhanced therapeutic efficiency. A model MDL conjugate is disclosed as well as method for the synthesis of the model conjugate.
申请公布号 US2008167370(A1) 申请公布日期 2008.07.10
申请号 US20070959947 申请日期 2007.12.19
申请人 SAFAVY AHMAD 发明人 SAFAVY AHMAD
分类号 A61K31/335;A61K47/48;A61K51/08 主分类号 A61K31/335
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