发明名称 TREATMENT OF DIABETES TYPE 2 WITH INHIBITORS OF DIPEPTIDYLPAPTIDASE IV
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to prevention and treatment of pancreatic diabetes type 2. To delay disease development or to provide early stage treatment such inhibitors of dipeptidylpeptidase IV are selected as to supply optimal inhibition constant. For this purpose (2S)-1 -((2'S)-2' -amino-3' ,3' -dimethylbutanoil) pyrrolidine-2-carbonitryl or its pharmaceutically accepted salt, or (2S)-l-((2'S)-2'-amino-5'-pyrazincarbonylaminopentanoil)pyrrolidine-2-carbonitryl or its pharmaceutically accepted salt. ^ EFFECT: improved prevention of diabetes and related complications. ^ 3 cl, 7 dwg, 3 ex
申请公布号 RU2328283(C2) 申请公布日期 2008.07.10
申请号 RU20030132687 申请日期 2002.04.10
申请人 FERRING BV 发明人 BROKA P'ER;SJUDR BEATRIS;OBER MISHEL' L.
分类号 A61K31/40;C07D277/04;A61K31/00;A61K31/401;A61K31/426;A61K31/4439;A61K31/497;A61K45/00;A61P3/10;C07D207/16;C07D401/12;C07D403/12 主分类号 A61K31/40
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