| 摘要 |
A collapsible filter element ( 105 ) for a transcatheter embolic protection device ( 100 ) comprises a collapsible filter body ( 30 ) which is movable between a collapsed stored position for movement through a vascular system and an expanded position for extension across a blood vessel such that blood passing through the blood vessel is delivered through the filter element ( 105 ). A proximal inlet portion of the filter body ( 30 ) has one or more inlet openings ( 117 ) sized to allow blood and embolic material enter the filter body ( 30 ) and a distal outlet portion of the filter body ( 30 ) has a plurality of outlet openings ( 119 ) sized to allow through-passage of blood, but to retain embolic material within the filter body ( 30 ). The filter body ( 30 ) is at least partially of laminate construction comprising a membrane ( 31 ) coated with a coating ( 32, 33 ) which is biocompatible, the thickness of the coating ( 32, 33 ) being from 4% to 40% of the thickness of the membrane ( 31 ). The coating ( 32, 33 ) may be of hydrophilic material. To facilitate retrieval of captured embolic material the distal portion and/or an intermediate portion of the filter membrane ( 31 ) may be stretchable. The filter body ( 30 ) may have regions of varying hardness or stiffness.
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