| 发明名称 |
ALTERED POLYPEPTIDES WITH INCREASED HALF-LIFE |
| 摘要 |
Polypeptides that are cleared from the kidney and do not contain in their original form a Fc region of an IgG are altered so as to comprise a salvage receptor binding epitope of an Fc region of an IgG and thereby have increased circulatory half-life. |
| 申请公布号 |
US2008166759(A1) |
申请公布日期 |
2008.07.10 |
| 申请号 |
US20070830537 |
申请日期 |
2007.07.30 |
| 申请人 |
GENENTECH, INC. |
发明人 |
PRESTA LEONARD G.;SNEDECOR BRADLEY R. |
| 分类号 |
C12P21/04;C07H21/04;C07K16/28;C12N5/00;C12N15/00 |
主分类号 |
C12P21/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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