| 摘要 |
Methods and apparatus efficiently purify blood or blood-derived fluid in a manner that reduces wasted fluid. A blood purification apparatus has a primary purification device and receives, at an input via a primary inlet line, a primary input fluid from a fluid source. The primary purification device partitions the input fluid into two output streams. The first output stream is enriched in larger components and the second output stream is enriched in smaller components. The first output stream is returnable to the source via a primary outlet line. A reservoir stores reservoir fluid and is positioned to accept the second output stream. A secondary purification device coupled to the reservoir receives reservoir fluid from the reservoir and partitions the reservoir fluid into two further streams: a third output stream enriched in larger components and a fourth output stream enriched in smaller components. The fourth output stream is coupled to merge with either the primary inlet line or to the first output stream. The third output stream is coupled to the reservoir. As a result, albumin or other intermediate weight molecules concentrates in the reservoir over time. Optionally, the apparatus may include a dialysis or adsorption module for removing low molecular weight toxins. |
