METHOD FOR THE FUNCTIONAL MEASUREMENT OF PLASMATIC THROMBODULINE ACTIVITY

摘要

The invention relates to a method for the in vitro measurement of the thromboduline functional activity, wherein said method comprises dosing in a biological medium, and from a biological sample, the thrombine-activation of C protein into activated C protein (PCa) in the presence of its co-factor or said thromboduline, said method comprising adding to the sample plasma the agents necessary for activating the C protein system, adding purified C protein and also adding a fibrin polymerisation inhibitor. The invention further relates to the application of said method in the detection of coagulation pathologies.