发明名称 TOPICAL USE OF NF-KB DECOYS FOR TREATING ATOPIC DERMATITIS
摘要 A pharmaceutical composition for performing treatment against a skin disease, the pharmaceutical composition comprising at least one decoy and a pharmaceutically acceptable carrier. The at least one decoy may be selected from the group consisting of an NF- kappa B decoy, a STAT-1 decoy, a GATA-3 decoy, a STAT-6 decoy, an AP-1 decoy and an Ets decoy. The at least one decoy may be an oligonucleotide including at least two decoys bonded to each other, the at least two decoys being selected from the group consisting of an NF- kappa B decoy, a STAT-1 decoy, a GATA-3 decoy, a STAT-6 decoy, an AP-1 decoy and an Ets decoy. The skin disease may be atopic dermatitis, psoriasis vulgaris, contact dermatitis, keloid, bedsore, ulcerative colitis, or Crohn's disease.
申请公布号 PT1362600(E) 申请公布日期 2008.07.09
申请号 PT20020711351T 申请日期 2002.02.06
申请人 ANGES MG, INC. 发明人 RYUICHI MORISHITA;MOTOKUNI AOKI;TOSHIO OGIHARA;YASUFUMI KANEDA;HIROSHIGE NAKAMURA
分类号 A61K48/00;A61K9/06;A61K31/711;A61K38/17;A61K47/06;A61K47/10;A61P17/00;A61P17/04;C12N15/113 主分类号 A61K48/00
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