摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an easy method for selectively producing an optically active compound useful as an intermediate for producing an antimicrobial agent. <P>SOLUTION: The compound is produced according to the following steps: reacting a compound represented by formula (I) (wherein R<SP>1</SP>is an alkyl group, a cyclic alkyl group, an aryl group or an aralkyl group, which may have a substituent) with a compound represented by formula (II): H<SB>2</SB>N-*R<SP>2</SP>(II) (wherein, *R<SP>2</SP>is a protective group of an amino group of a single stereoisomer) or a salt thereof, and a cyanizing agent to provide diastereomers represented by formula (III), and precipitating one of the diastereomers as a solid. <P>COPYRIGHT: (C)2004,JPO</p> |