发明名称 |
CHEMO-ENZYMATIC PROCESS FOR PREPARING ESCITALOPRAM |
摘要 |
<p>A process for preparing an intermediate for synthesizing escitalopram and the pharmaceutically acceptable salts thereof from 4-(4-dimethylamino)-1-(4'-fluorophenyl)-1-(hydroxybutyl)-3-(acyloxymethyl)benzonitrile is described. The process involves converting said intermediate into the (S+) enantiomer of citalopram by means of enzymatic enantiomeric resolution.</p> |
申请公布号 |
SI1733042(T1) |
申请公布日期 |
2008.10.31 |
申请号 |
SI20050030329T |
申请日期 |
2005.04.07 |
申请人 |
ADORKEM TECHNOLOGY SPA |
发明人 |
COTTICELLI GIOVANNI;ROCCHIETTI SILVIA;TERRENI MARCO;PREGNOLATO MASSIMO;SALVETTI RAUL |
分类号 |
C12P41/00 |
主分类号 |
C12P41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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