发明名称 Bone cement and X-ray contrast agent and methods of manufacturing the same
摘要 <p>Use is claimed of barium- and/or zirconium- and/or other X-ray-opaque element-containing (co)polymers as X-ray contrast agents in bone cements. Independent claims are also included for (1) an X-ray contrast agent comprising either (i) a (co)polymer with a chemically-bonded compound of an X-ray-opaque element or (ii) approximately spherical (co)polymer particles with dispersed X-ray-opaque 3-15nm inorganic nanoparticles obtained by (especially suspension) polymerization in presence of the nanoparticles, the nanoparticles being (almost) wholly covered by the (co)polymer; (2) a bone cement with polymer and monomer components, the polymer component comprising the above X-ray contrast agent; and (3) production of the bone cements involving addition of an X-ray-opaque element-containing polymer and/or monomer during preparation of the (co)polymer.</p>
申请公布号 EP1782845(B1) 申请公布日期 2008.12.17
申请号 EP20070000986 申请日期 2003.04.25
申请人 HERAEUS KULZER GMBH 发明人 KUEHN, KLAUS-DIETER
分类号 A61L24/02;A61L27/00;A61K49/00;A61K49/04;A61L24/00;A61L24/04 主分类号 A61L24/02
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