| 摘要 |
<p>The present invention relates to a method for the chemical separation of the enantiomers of 1,1'-spirobiindane-6,6'-diol derivatives comprising providing a racemic chiral 1,1'-spirobiindane-6,6'-diol derivative, reacting a nonracemic chiral component with the racemic chiral 1,1'-spirobiindane-6,6'-diol derivative to afford a mixture of diastereomeric diesters, separating the mixture of diastereomeric diesters to provide a substantially pure individual diastereomeric diester, and chemically removing the ester groups from the substantially pure individual diastereomeric diester to provide a nonracemic chiral 1,1'-spirobiindane-6,6'-diol derivative.</p> |
