发明名称 Derivatives of 4-(imidazol-5-yl)-2-(4-sulfoanilino)pyrimidine with CDK inhibitory activity
摘要 Compounds of the formula (I): wherein R1, R2, R3, R4, R5 and p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.
申请公布号 US7465728(B2) 申请公布日期 2008.12.16
申请号 US20040507081 申请日期 2004.09.09
申请人 ASTRAZENECA AB 发明人 NEWCOMBE NICHOLAS JOHN;THOMAS ANDREW PETER
分类号 C07D403/04;A61K31/506;A61K31/5377;A61K31/63;A61P1/00;A61P1/16;A61P1/18;A61P9/00;A61P9/10;A61P11/00;A61P13/08;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P17/12;A61P17/14;A61P19/00;A61P19/02;A61P19/08;A61P21/00;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07D401/14;C07D403/14;C07D405/14;C07D413/04;C07D413/14;C07D417/14 主分类号 C07D403/04
代理机构 代理人
主权项
地址