发明名称 Amide derivative
摘要 There is provided a pharmaceutical drug, particularly a novel compound useful for prophylaxis or a therapeutic treatment of various diseases involving infections with viruses of the herpesvirus family, specifically various herpesvirus infections such as varicella (chicken pox) via varicella zoster virus, varicella zoster via recurrent infection with latent varicella zoster virus, herpes labialis and herpes encephalitis via HSV-1 and genital herpes via HSV-2 infection. An N-{2-[(4-substituted phenyl)amino]-2-oxoethyl}tetrahydro-2H-thiopyran-4-carboxamide derivative, of which phenyl group is substituted at position 4 with a specific 5- or 6-membered heteroaryl group, and a salt thereof have an effective anti-virus activity, and the oral administration thereof at a low dose enabled the therapeutic treatment of the above diseases.
申请公布号 US7465748(B2) 申请公布日期 2008.12.16
申请号 US20040567565 申请日期 2004.08.05
申请人 ASTELLAS PHARMA INC.;RATIONAL DRUG DESIGN LABORATORIES 发明人 KONTANI TORU;MIYATA JUNJI;HAMAGUCHI WATARU;KAWANO TOMOAKI;KAMIKAWA AKIO;SUZUKI HIROSHI;SUDO KENJI
分类号 A61K31/41;A61P31/22;C07D271/06;C07D335/02;C07D413/12 主分类号 A61K31/41
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