TRANSGLUTAMINASE INHIBITOR COMPRISING EGCG AND A METHOD FOR PRODUCING THEREOF

摘要

A pharmaceutical composition comprising a transglutaminase inhibitor containing EGCG(epigallocatechin gallate) is provided to cure the disease caused by the increment of transglutaminase activity. The transglutaminase inhibitor is comprised of the epigallocatechin gallate(EGCG) or its derivatives. The activity of transglutaminase is suppressed by using EGCG or its derivative. The pharmaceutical composition for treating the disease caused by the increment of transglutaminase activity comprises the epigallocatechin gallate(EGCG) or its derivatives, wherein the disease is nervous system disorders including Alzheimer's disease, Huntington's disease and Parkinson's disease or cancer.