| 摘要 |
A biomarker for diagnosing lung cancer is provided to be specifically over-expressed in endothelial cells derived from a lung cancer tissue, thereby being useful for diagnosing the lung cancer and evaluating the progress state of a disease and prognosis of treatment. A composition for diagnosing lung cancer comprises an antibody specifically bound to a protein selected from the group consisting of COPG(coatomer protein complex subunit gamma), IGHA-1(immunoglobulin heavy constant alpha-1), IVD(isovaleryl coenzyme A dehydrogenase), TIbeta/gamma(thymopoietin isoforms beta/gamma), MAPRC-2(membrane associated progesterone receptor component 2), RPS4X(ribosomal protein S4, X isoform), NDUFA5(NADH dehydrogenase(ubiquinone) 1 alpha subcomplex 5), RPS8(ribosomal protein S8), 7kDa protein, CSA(coatomer subunit alpha), CYFIP-1(cytoplasmic FMR1 interacting protein 1), SERPINH1(47kDa heat shock protein precursor), TABCSFBI-2(transporter 2, ATP-binding cassette, subfamily B isoform 2), SF3-S1(splicing factor 3 subunit 1), SILUCTH-5(splicing isoform long of ubiquitin carboxyl-terminal hydrolase 5), EF1-beta(elongation factor 1-beta), IGKC(Ig Kappa chain C region), HCV1R HG3 precursor(similar to Ig heavy chain V-I region HG3 precursor) and OCIAP(ovarian carcinoma immunoreactive antigen-like protein), or a polypeptide specifically bound to the protein, or a primer or a probe specifically bound to a gene encoding the protein. |
