摘要 |
PROBLEM TO BE SOLVED: To provide a commercially useful perfluoroalkylation reaction exhibiting high optical selectivity. SOLUTION: This method for producing perfluoroalkylalcohols comprises reacting asymmetric perfluoroalkylsilanes with a carbonyl-containing compound in the presence of a chiral phase-transfer catalyst and a tetraalkylammonium halide, followed by deprotecting. COPYRIGHT: (C)2009,JPO&INPIT
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