| 摘要 |
The present invention relates to a vaccine composition for the prevention and treatment of allergic disease comprising irradiated ovalbumin as an effective ingredient, more precisely a method for preparing an immunogen of a vaccine for the prevention and treatment of allergic disease using the irradiated ovalbumin which is separated and purified from the albumen of an egg, a vaccine composition for the prevention and treatment of allergic disease comprising the irradiated ovalbumin as an effective ingredient, and a method for the prevention and treatment of allergic disease using the vaccine comprising the irradiated ovalbumin. In the mouse vaccinated with the irradiated ovalbumin, humoral and cell mediated immune responses were both reduced, suggesting that allergic reaction was inhibited. Thus, the composition of the present invention can be effectively used as a vaccine for the prevention and treatment of allergic disease.
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