发明名称 |
METHODS OF GENERATING PLURIPOTENT CELLS FROM SOMATIC CELLS |
摘要 |
Disclosed herein are methods to select for the generation of mouse and human pluripotent stem cells during developmental reprogramming. The methods described herein relate to the selection of induced pluripotent stem cells, i.e., pluripotent stem cells generated or induced from differentiated cells without a requirement for genetic selection. Described herein are particular embodiments for selection of reprogrammed cells based on 1) colony morphology, or 2) X chromosome reactivation in female cells. |
申请公布号 |
WO2008151058(A2) |
申请公布日期 |
2008.12.11 |
申请号 |
WO2008US65384 |
申请日期 |
2008.05.30 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;HOCHEDLINGER, KONRAD;MAHERALI, NIMET |
发明人 |
HOCHEDLINGER, KONRAD;MAHERALI, NIMET |
分类号 |
C12N5/074 |
主分类号 |
C12N5/074 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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