发明名称 |
PROCESS FOR FORMING SOLID ORAL DOSAGE FORMS OF ANGIOTENSIN II RECEPTOR ANTAGONISTS |
摘要 |
A method for producing granules of an angiotensin II receptor antagonist or a pharmaceutically acceptable salt thereof, which comprises: a) mixing the angiotensin II receptor antagonist or pharmaceutically acceptable salt thereof with a melt granulating agent to form a mixture; b) elevating the temperature of the mixture to the melting point of the melt granulating agent to form a solid dispersion of the angiotensin II receptor antagonist in the melt granulating agent; and c) cooling the solid dispersion to form granules; wherein the melt granulating agent is the only granulating agent used to form the granules. |
申请公布号 |
WO2008149338(A2) |
申请公布日期 |
2008.12.11 |
申请号 |
WO2008IL00732 |
申请日期 |
2008.05.29 |
申请人 |
DEXCEL LTD.;SCHLINGER, RON;AVRAMOFF, AVI |
发明人 |
SCHLINGER, RON;AVRAMOFF, AVI |
分类号 |
A61K9/16;A61K9/48;A61K9/50;A61K31/41 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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