发明名称 Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta,Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-HeptanoicAcid Calcium Salt (2:1)
摘要 Novel forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease.
申请公布号 US2008306282(A1) 申请公布日期 2008.12.11
申请号 US20050572333 申请日期 2005.07.11
申请人 发明人 KRZYZANIAK JOSEPH F.;LAURENCE GEORGE M.;PARK AERI;QUACKENBUSH KEVIN J.;REYNOLDS MARIE L.;ROSE PETER R.;WOODS TIMOTHY A.
分类号 C07D207/34 主分类号 C07D207/34
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