BIFUNCTIONAL PREDICTORS OF CANCER TREATMENT SENSITIVITY AND RESISTANCE
摘要
The present invention provides the identification of genes that are expressed in tumors to indicate responsiveness or resistance to an agent or class of agents. More particularly, these genes show expression associated with responsiveness to one agent or class of agents is inversely related to expression in association with another class of agents. One or more of theses genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by the responsive agent as well as to identify tumors that should avoid treatment by the resistant agent.
申请公布号
WO2008073629(A3)
申请公布日期
2008.12.11
申请号
WO2007US83651
申请日期
2007.11.05
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;NUVERA BIOSCIENCES, INC.;HATZIS, CHRISTOS;SYMMANS, FRASER, W.;PUSZTAI, LAJOS
发明人
HATZIS, CHRISTOS;SYMMANS, FRASER, W.;PUSZTAI, LAJOS