摘要 |
The invention relates to anti-VEGF polypeptides and antibody single variable domains (dAbs) that are resistant to degradation by a protease, as well as antagonists comprising these. The polypeptides, dAbs and antagonists are useful for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient, as well as for treating cancer and inflammatory disease, such as arthritis. |
申请人 |
DOMANTIS LIMITED;STEWARD, MICHAEL;PUPECKA, MALGORZATA;TOMLINSON, IAN;ENEVER, CAROLYN;JESPERS, LAURENT;BATUWANGALA, THIL DINUK |
发明人 |
STEWARD, MICHAEL;PUPECKA, MALGORZATA;TOMLINSON, IAN;ENEVER, CAROLYN;JESPERS, LAURENT;BATUWANGALA, THIL DINUK |