| 摘要 |
The invention relates to novel blockers for pharmaceutical compositions exhibiting antihistaminic activity and to a method for treating and preventing the development of different allergic diseases. The inventive blockers are in the form of substituted 2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indoles of general formula (1) and the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1 is an aminogroup substituent selected from optionally substituted C1-C5 alkyl, optionally substituted C2-C4 alkenyl, optionally substituted C1-C5 alkinyl, carbamoyl, thiocarbamoyl and a substituted mercapto group R2 i |
| 申请人 |
ALLA CHEM, LLC;IVASHCHENKO, ANDREY ALEXANDROVICH;IVASHCHENKO, ALEXANDER VASILIEVICH;TKACHENKO, SERGEY YEVGENIEVICH;FROLOV, YEVGENIY BORISOVICH;MITKIN, OLEG DMITRIEVICH;KRAVCHENKO, DMITRI VLADIMIROVICH;OKUN, ILYA MATUSOVICH;SAVCHUK, NIKOLAY FILIPPOVICH |
发明人 |
IVASHCHENKO, ANDREY ALEXANDROVICH;IVASHCHENKO, ALEXANDER VASILIEVICH;TKACHENKO, SERGEY YEVGENIEVICH;FROLOV, YEVGENIY BORISOVICH;MITKIN, OLEG DMITRIEVICH;KRAVCHENKO, DMITRI VLADIMIROVICH;OKUN, ILYA MATUSOVICH;SAVCHUK, NIKOLAY FILIPPOVICH |
