The present invention relates to 5-substituted hydantoins, a process for the preparation of 5-substituted hydantoins and the use of 5-substituted hydantoins in the preparation of enantiomerically enriched a-amino acids. Furthermore, the present invention relates to the preparation of pharmaceutically active products such as perindopril and ramipril using the novel 5-substituted hydantoins.
申请公布号
WO2008148755(A2)
申请公布日期
2008.12.11
申请号
WO2008EP56841
申请日期
2008.06.03
申请人
DSM IP ASSETS B.V.;SARAKINOS, GEORGIOS;BOESTEN, WILHELMUS HUBERTUS JOSEPH;HEEMSKERK, DENNIS;LANGE, DE, BEN
发明人
SARAKINOS, GEORGIOS;BOESTEN, WILHELMUS HUBERTUS JOSEPH;HEEMSKERK, DENNIS;LANGE, DE, BEN