摘要 |
Methods of freezing, thawing and imaging a biological sample, one or more times, in a manner sufficient to freeze, thaw, and/or image the biological sample, while maintaining the structural integrity and/or viability of the sample are provided. Aspects of embodiments of the methods include freezing, thawing and/or imaging a biological sample under pressure in a manner sufficient to maintain the structural integrity and/or viability of the sample. Also provided are devices and systems for use in practicing the methods. |