A polymer electrolyte fuel cell is formed by a fuel cell stack assembled by cramping a plurality of layered single cell modules via a pair of end plates by a plurality of cramping members. The polymer electrolyte fuel cell includes: a plurality of first elastic members each arranged between the cramping member and the end plate; and a plurality of second elastic members each arranged between the end plate and the fuel cell stack end portion. The respective second elastic members are arranged on the end plate surface equivalent to an electrode portion of a film electrode assembly in the respective single cell modules while the respective first elastic members are arranged on the end plate surface equivalent to an arrangement region of a seal member arranged between the rim portion of the film electrode assembly and a pair of separator plates.