发明名称 |
WNT COMPOSITIONS AND METHODS OF USE THEREOF |
摘要 |
Methods and compositions are provided for the therapeutic use of Wnt proteins, where the Wnt protein is inserted in the non-aqueous phase of a lipid structure. In some embodiments the Wnt protein is presented in its active conformation on an outer liposome membrane or micelle. Pharmaceutical compositions of the present invention can be administered to an animal for therapeutic purposes. In some embodiments of the invention, the compositions are administered locally, e.g. by injection at the site of an injury. For certain conditions it is desirable to provide Wnt activity for short periods of time, and an effective dose will be administered over a defined, short period of time. |
申请公布号 |
WO2008109119(A3) |
申请公布日期 |
2008.12.11 |
申请号 |
WO2008US02967 |
申请日期 |
2008.03.05 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;HELMS, JILL;NUSSE, ROELAND;KIM, JAEBEOM;LEUCHT, PHILIPP |
发明人 |
HELMS, JILL;NUSSE, ROELAND;KIM, JAEBEOM;LEUCHT, PHILIPP |
分类号 |
A61K38/00;A61P19/00;A61P19/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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