发明名称 PROCESS FOR THE PREPARATION OF 3-SPIRO[CYCLOHEXAM-1,3'-[3H]INDOLIN-2'-ONE] DERIVATIVES
摘要 The invention relates to a process for the preparation of a compound of the formula (I) by reacting a compound of the formula (II) with a compound of th e formula (III) characterised by dissolving the compounds of the formula (II) and formula (III) in a water-inmiscible organic solvent in the presence of a phase transfer catalyst, reacting with a.) an aqeuos solution of a base, or b.) a base in solid form directly and if desired transforming the compound o f formula (I) thus obtained into its salt.
申请公布号 CA2453946(C) 申请公布日期 2008.12.09
申请号 CA20022453946 申请日期 2002.07.25
申请人 SANOFI-SYNTHELABO 发明人 HAJDU, FELIX;SZVOBODA, GYORGYNE;HERMECZ, ISTVAN;SANTANE CSUTOR, ANDREA;SZOMOR, TIBORNE;NAGY, LAJOS;GONCZI, CSABA;CSIKOS, EVA;HEJA, GERGELY;HEJA, GERGELYNE;MAJLATH, CSILLA
分类号 C07D413/12;A61P7/10;A61P9/00;C07B61/00;C07D209/96 主分类号 C07D413/12
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