发明名称 Method and system for optimizing minigenes and peptides encoded thereby
摘要 The invention relates to the field of biology. In particular, the invention relates to a method and system for designing optimized multi-epitope vaccines having selected combinations of amino acid insertions at the junctions of the multi-epitope constructs so as to minimize the number of junctional epitopes and provide vaccines with increased immunogenicity.
申请公布号 US7462354(B2) 申请公布日期 2008.12.09
申请号 US20010894018 申请日期 2001.06.27
申请人 PHARMEXA INC. 发明人 SETTE ALESSANDRO;CHESNUT ROBERT;LIVINGSTON BRIAN D.;BAKER DENISE MARIE;NEWMAN MARK J.
分类号 A61K39/00;C12N15/09;A61K39/21;A61K39/29;A61K39/295;A61K48/00;A61P43/00;C07K14/00;C07K14/115;C07K14/16;C12N15/86;G06F17/50;G06F19/16;G06F19/18;G06F19/22;G06F19/24 主分类号 A61K39/00
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