| 摘要 |
The invention relates to triazolopyridine carboxamide derivatives of general formula (I) in which X represents a hydrogen atom, a halogen atom, a (C1-C6)alkyl, (C1-C6)alkoxy, halo(C1-C6)alkyl, S(O)mR', hydroxyl or cyano group, A is absent or else represents a bond, an oxygen atom, a sulphur atom, an NR, C(O)NR' or SO2NR' group, a (C1-C2)alkylene group, or a (C2)alkenyl group, R1 and R2 represent, independently of one another, one or more groups chosen from a hydrogen atom, a (C1-C6)alkyl group, a (C1-C6)alkoxy group, a (C3-C7)cycloalkyl group, a (C3-C7)cycloalkyl-(C1-C6)alkyl group, a (C3-C7)cycloalkyl(C1-C6)alkoxy group, a halogen atom, a cyano group, a C(O)R', C(O)OR', C(O)NR10R20 or NO2 group, an NR10R20 or NR10C(O)-R20 group, the (C1-C6)alkyl and (C1-C6)alkoxy groups being optionally substituted by one or more atoms or groups chosen independently from one another from halogen atoms, and hydroxyl, amino or NR10R20 groups. Preparation method and therapeutic use thereof. |
