DITHIAZOLVERBINDUNGEN, MATRIX-METALLOPROTEASE-INHIBITOREN UND ZUBEREITUNGEN FÜR DIE ÄUßERLICHE ANWENDUNG AUF DER HAUT

摘要

A dithiazole compound or a salt thereof expressed by formula (I): wherein R1, is hydrogen atom, alkyl, etc.; R2 is hydrogen atom, hydroxy, alkyl, aryl, arylalkoxy, arylalkyl, etc.; R3 is one group of formulae (II), (III) and (IV): This compound has an excellent inhibiting action on matrix metalloprotease (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions.