IMPROVED SYNTHESIS OF (2S-CIS)-2-(BROMOMETHYL)-2-(4-CHLOROPHENYL)-1,3 DIOXOLANE-4-METHANOL METHANESULFONATE(ESTER)
摘要
<p>The present invention relates to an improved process for the preparation of (2S-cis)-2- (bromomethyl)-2-(4-chlorophenyl )-1,3-dioxolane-4-methanol methanesulfonate(ester), a key intermediate for the preparation of the apoB secretion/MTP inhibitor mitratapide.</p>
申请公布号
WO2008145605(A1)
申请公布日期
2008.12.04
申请号
WO2008EP56355
申请日期
2008.05.23
申请人
JANSSEN PHARMACEUTICA NV;FILLIERS, WALTER FERDINAND MARIA;VERSTAPPEN, WALTER LOUIS ANTOINE;BELLINKX, RONNY
发明人
FILLIERS, WALTER FERDINAND MARIA;VERSTAPPEN, WALTER LOUIS ANTOINE;BELLINKX, RONNY