| 发明名称 |
R-SPONDIN COMPOSITIONS AND METHODS OF USE THEREOF |
| 摘要 |
The invention provides for a method for screening compounds that bind to and modulate a regulator of Wnt signaling, R-spondin 4. The invention further provides for methods for diagnosing a keratin-related abnormality, such as anonychia congenital, in a subject. The invention also provides for isolated RSPO4 mutant molecules.
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| 申请公布号 |
WO2008020942(A3) |
申请公布日期 |
2008.12.04 |
| 申请号 |
WO2007US16197 |
申请日期 |
2007.07.17 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;CHRISTIANO, ANGELA, M. |
发明人 |
CHRISTIANO, ANGELA, M. |
| 分类号 |
A61K35/00;A61K9/00;A61K36/00 |
主分类号 |
A61K35/00 |
| 代理机构 |
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