| 发明名称 |
Auristatins Having an Aminobenzoic Acid Unit at the N Terminus |
| 摘要 |
Auristatin-type peptides are disclosed which are highly cytotoxic, synthetically accessible, and can be conjugated to antibodies and other ligands.
|
| 申请公布号 |
US2008300192(A1) |
申请公布日期 |
2008.12.04 |
| 申请号 |
US20050667437 |
申请日期 |
2005.11.14 |
| 申请人 |
SEATTLE GENETICS, INC. |
发明人 |
DORONINA SVETLANA O.;MENDELSOHN BRIAN A. |
| 分类号 |
A61K38/06;A61K38/05;A61P35/00;A61P37/00;C07D207/16;C07D403/12;C07K5/083;C12N5/06 |
主分类号 |
A61K38/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
