IMPLANTABLE DEVICES CONTAINING NUCLEAR RECEPTOR LIGANDS FOR THE TREATMENT OF VASCULAR AND RELATED DISORDERS

摘要

The present invention is directed to implantable devices (e.g., drug-delivery stents) containing nuclear receptor ligands. The nuclear receptor ligands may be, inter alia, PPAR ligands or retinoids. The invention also provides for the use of the nuclear receptor ligand-containing devices in treating or preventing vascular disorders (e.g., restenosis) and related disorders.