The present invention provides a novel method for solid-phase phosphoramidite based synthesis of borane phosphonate DNA. Also provided are novel phosphoramidite molecules, novel extended length borane phosphonate nucleic acid compounds, and methods of use thereof.
申请公布号
WO2007106413(A3)
申请公布日期
2008.12.04
申请号
WO2007US06132
申请日期
2007.03.09
申请人
REGENTS OF THE UNIVERSITY OF COLORADO;MCCUEN, HEATHER, BRUMMEL;SIERZCHALA, AGNIESZKA, B.;CARUTHERS, MARVIN, H.
发明人
MCCUEN, HEATHER, BRUMMEL;SIERZCHALA, AGNIESZKA, B.;CARUTHERS, MARVIN, H.