| 摘要 |
Compounds of the formula I give a cooling sensation to the mouth and skin: In Formula I, m is 0 or 1; X is -(CH2)n-R, where n is 0 or 1 and R is selected from -OR'. -COOH, -COOR'', -SO2NH2, -CHO, -COR''', and -CN, R' being selected from H and C1-C3 straight- and branched-chain alkyl. R'' from C1-C4 straight- and branched-chain alkyl and R''' from C1-C3 straight- and branched-chain alkyl: Y is selected from H, -COOH and -OR''', where R''' has the significance previously referred to; and Z is H; with the provisos that (iii) When Y is H and X is any of the abovementioned significances, except -CN and -COOH, X is in the 4-position; (iv) when Y has a significance other than H, it is in the 5-position when X is in the 2-position and in the 6-position when X is in the 3-position. The compounds give a cooling sensation that can be more powerful than the best current commercial materials.
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