Device for enhancing transdermal agent flux

摘要

The present invention is directed to an applicator for applying a member having a plurality of skin piercing microprotrusions to skin, the applicator comprising a head for applying a skin piercing force to the member, the head having a surface adapted to enlarge the member, the surface having a shape selected from the group consisting of convex, curved, cylindrical, and flat.

<Paragraphs id="pa02" num="0002" xmlns:base="http://www.sipo.gov.cn/XMLSchema/base">The head is capable of being adapted to enlarge the member and impact it against the skin. The present invention also provide the aforementioned applicator for use in a method of piercing the skin with a plurality of skin piercing microprotrusions.