| 摘要 |
1,212,055. Compositions comprising heparinoid complexes. CANADA PACKERS Ltd. 25 June, 1968 [3 July, 1967], No. 30240/68. Heading A5B. [Also in Division C3] The active ingredient compositions having blood anticoagulant and antilipemic effects is either (1) a complex of a heparinoid (i.e. heparin, a derivative thereof or a synthetically sulphated polysaccharide such as dextran sulphuric acid) with (a) a non-toxic amino acid having a pI below about 9.7 or (b) a non- toxic organic base having a pKC in the range 9.5-12.5 or (2) a complex of heparinic acid with a non-toxic organic base having a pKC above 7.0 and in which a portion of the acid groups are satisfied by a strongly basic cation (see Div. C3). The composition is intended for absorption through mucous membranes and may take the form of enteric-coated capsules, buccal or sublingual tablets or powders, a suppository or a nasal spray.
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