| 发明名称 |
MELUSIN, A MUSCLE SPECIFIC PROTEIN, AS A DRUG TARGET FOR PREVENTION AND TREATMENT OF HEART FAILURE, AND APPLICATIONS THEREOF |
| 摘要 |
The present invention concerns non-human transgenic animals as model study for human pathologies, being transgenic for having altered melusin expression. The non-human transgenic animals are to be used as models to study heart pathologies and provide therapies thereof, wherein the heart pathologies are heart failure, and in particular diluted cardiomyopathy. |
| 申请公布号 |
EP1575354(B1) |
申请公布日期 |
2008.12.03 |
| 申请号 |
EP20020808278 |
申请日期 |
2002.12.19 |
| 申请人 |
UNIVERSITA' DEGLI STUDI DI TORINO |
发明人 |
BRANCACCIO, MARA;SILENGO, LORENZO;ALTRUDA, FIORELLA;LEMBO, GIUSEPPE;FRATTA, LUIGI;TARONE, GUIDO |
| 分类号 |
A01K67/027;A61K38/17;A61K48/00;C07K14/46;C12N15/85;G01N33/50 |
主分类号 |
A01K67/027 |
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