| 发明名称 |
AMINOOXY-MODIFIED OLIGONUCLEOTIDES |
| 摘要 |
Nucleotide compositions containing aminooxy moieties are provided. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligonucleotide is modified to include an aminooxy moiety. |
| 申请公布号 |
CA2278715(C) |
申请公布日期 |
2008.12.02 |
| 申请号 |
CA19982278715 |
申请日期 |
1998.02.13 |
| 申请人 |
ISIS PHARMACEUTICALS INC. |
发明人 |
COOK, PHILLIP DAN;KAWASAKI, ANDREW MAMORU;MANOHARAN, MUTHIAH |
| 分类号 |
C07H21/00;A01N43/04;A61K31/7072;A61K31/7076;A61P43/00;C07H15/203;C07H19/04;C07H19/048;C07H19/06;C07H19/16 |
主分类号 |
C07H21/00 |
| 代理机构 |
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代理人 |
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