| 摘要 |
The present invention relates to compounds of the general formula (Ih) or pharmaceutically acceptable salts thereof with an acid or a base, or pharmaceutically acceptable prodrugs or a stereoisomer thereof, (Ih) wherein A is NR2, S or O; R3a is H, OH, SH, NH2,-C(NR7)NR7'R8,-(CH2)paryl,-(CH2)PNR7R8,-C(O)NR7R8,-N=CR7R8,-NR7C(O)R8, alkyl, cycloalkyl, hydroxyalkyl, haloalkyl, haloalkyloxy, alkoxy, alkylamino, hydroxyalkylamino, halogen, aryl, or heteroaryl; R3 is H,-C(0)NRaRb, halogen, alkyl, haloalkyl, aryl, heteroaryl, OH, SH, NR4' OR5', NH2, hydroxyalkylamino, alkylamino, alkoxy, cycloalkyl, hetero-cycloalkyl, hydroxyalkyl, or haloalkyloxy; X is NR2', O, or S; Z is N or CR2'. ® KIPO & WIPO 2009
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