发明名称 Methods and compostions for treatment of central and peripheral nervous system disorders and novel compounds useful therefor
摘要 Disclosed is a crystalline form of (S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decane-3-one (AF267B) having the configuration (I). Also disclosed is the use of the crystalline form above and pharmaceutically acceptable salts thereof in the preparation of a pharmaceutical composition for stimulating the M1 muscarinic receptor.
申请公布号 NZ560368(A) 申请公布日期 2008.11.28
申请号 NZ20030560368 申请日期 2003.05.01
申请人 ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH 发明人 FISHER, ABRAHAM;BAR-NER, NIRA;KARTON, YISHAI
分类号 C07D491/107;A61K31/438;A61K31/439;A61K45/00;A61K47/06;A61P1/00;A61P1/04;A61P1/10;A61P1/12;A61P3/04;A61P9/00;A61P11/00;A61P11/06;A61P13/08;A61P13/10;A61P15/02;A61P17/16;A61P19/02;A61P25/00;A61P25/02;A61P25/04;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P27/02;A61P27/04;A61P27/06;A61P29/00;A61P37/00;A61P37/04;A61P43/00;C07D;C07D471/10;C07D491/10;C07D491/20;C07D513/10;(IPC1-7):C07D513/10;C07D221/20;A61K31/452 主分类号 C07D491/107
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