| 发明名称 |
RNAi MODULATION OF THE BCR-ABL FUSION GENE AND USES THEREOF |
| 摘要 |
The invention relates to compositions and methods for modulating the expression of Bcr-Abl, and more particularly to the down-regulation of Bcr-Abl mRNA and Bcr-Abl protein levels by oligonucleotides via RNA interference, e.g., chemically modified oligonucleotides.
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| 申请公布号 |
US2008293662(A1) |
申请公布日期 |
2008.11.27 |
| 申请号 |
US20080171291 |
申请日期 |
2008.07.10 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
HADWIGER PHILIPP;VORNLOCHER HANS-PETER;VAN DER KUIP HEIKO |
| 分类号 |
A61K31/70;A61P31/00;C07H21/04 |
主分类号 |
A61K31/70 |
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